The use of non-aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (brand names: Advil, Motrin) appears to reduce one's risk in developing PD. In a research group of 146,948 users of ibuprofen who were followed for an average time of 8.5 years, there were only 413 participants who had developed Parkinson's Disease. According to results of the study, this translates into a 35 percent lower risk of developing PD for those who take ibuprofen but do not take it regularly, or a 38 percent lower risk of developing PD for those who take ibuprofen daily, or a 27 percent lower risk of developing PD for those who take ibuprofen twice weekly. The incidence of PD and men and women appears to be equally distributed. Additionally, it does not appear there are any benefits to the long-term use of ibuprofen.
Read more about it in the article Ibuprofen May Lower Risk Of Parkinson's Disease, or in the article Ibuprofen May Help Parkinson's.
One must be cautioned that these are preliminary results, and should not be construed to mean that use of ibuprofen is sanctioned by the researchers. The mechanisms by which the use of nonsteroidal anti-inflammatory drugs (NSAIDs) help prevent or lessen the likelihood of PD are not known.
