Protein Interaction can Explain Neurological Conditions

Summary: Abnormal, or fatal, interactions between the a-syn protein, which is involved in Alzheimer's disease, and the Abeta amyloid, which is linked to the plaque associated with Alzheimer's disease, can form hybrid, unique complexes. The hybrid complexes created can result in combined neurodegenerative diseases, such as Parkinson's disease.

Comment: This research shows the relationship between Alzheimer's and Parkinson's, and explains the higher risk of those with Alzheimer's also developing Parkinson's. The protein models developed can show scientists how to better prevent the conditions, and improve the symptoms of the conditions. The research team also developed a method of dynamic modeling, which allows researchers to model accurately at the atomic level.

Read article - Science Daily September 7, 2008