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Oct '0715

Cannabis Hold Promise as Parkinson's Therapy

by Kristine DaynesTreatments

Summary: Cannabis (marijuana) and endocannabinoids affect several biological processes, including neuroprotection.

Comment: This technical article discusses the scientific and therapeutic contributions of the cannabis plant.

Oct '079

Several Defects Impair Drivers with Parkinson's

by Kristine DaynesLifestyle

Summary: Several defects are more significant than impaired motor skills in making it unsafe for some people with Parkinson's disease to drive. These include errors in judgment, easy distractibility, and an inability to multitask.

Comment: Even patients with relatively mild disease perform significantly worse than control drivers on all motor, cognitive, visual, and driving tests.

Oct '078

Relatives of Parkinson's Patients at Risk for Dementia

by Kristine DaynesResearch

Summary: Relatives of patients with Parkinson's disease are more likely than others to develop symptoms of dementia. Researchers propose the presence of shared risk factors.

Comment: Further research will be required to identify whether the shared risk factors are genetic or related to a shared lifestyle.

Oct '078

New Firm Innovates Bone Marrow Stem Cell Research

by Kristine DaynesTreatments

Summary: An Israeli company hopes to market stem cell treatments for neuorological disorders such as Parkinson's disease. Instead of using embryonic stem cells, BrainStorm Cell Therapeutics uses stem cells from the bone marrow of adults.

Comment: The company plans to start studies in Israle and the U.S. within a year. It is likely that the company will be trading on Nasdaq before it's treatments will be available commercially.

Oct '078

Levodopa and Pain Threshold in PD Patients

by Kristine DaynesResearch

Summary: People with Parkinson's disease (PD) have a lower pain threshold than their peers. However, in a clinical study, levodopa increased the pain threshold of subjects with PD compared with healthy subjects who receive the same dose.

Comment: The findings confirm that patients with PD have an abnormal pain threshold.

Oct '075

Two Enzymes Protect Mitochondria, Prevent PD

by Kristine DaynesResearch

Summary: Two cell enzymes cooperate to prevent a break-down of mitochondria which could otherwise lead to Parkinson's disease.

Comment: This new understanding will help scientists develop targeted therapies for Parkinson's disease.

Oct '072

Parkinson's, Alzheimer's Have Distinctly Different Dementia

by Kristine DaynesResearch

Summary: Dementia is patients with Parkinson's disease is distinctly different from symptoms in patients with Alzheimer's. Parkinson's patients tend to have poor attention, while Alzheimer's patients have worse memory.

Comment: The different cognitive profiles between AD and PD patients suggest the diseases are caused by different pathologies.

Sep '0727

Computer Model Simulates Balance

by Kristine DaynesResearch

Summary: Scientists at Emory University have developed a computer model that simulates how the nervous system communicates with muscles to move muscles and control balance.

Comment: The findings may eventually help diagnose and treat balance problems associated with Parkinson's disease and multiple sclerosis.

Sep '0718

Gene Mutation Linked to Onset Before Age 50

by Kristine DaynesResearch

Summary: Mutations in the glucocerebrosidase (GBA) gene nearly triple the likelihood of developing Parkinson's disease and double the risk of onset before age 50.

Comment: Mutations in the GBA gene also cause Gaucher's disease, a rare disorder.

Sep '0712

More People to Die of Parkinson's Disease

by Kristine DaynesResearch

Summary: As life expectancy rises in the U.S., and as death rates for diseases like cancer and heart disease drop, more people will die of Parkinson's disease. It is now the 14th leading cause of death.

Comment: These statistics are part of a comprehensive report by the Centers for Disease Control and Prevention.

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